Inappropriate antidiuretic hormone secretion in Wernicke's encephalopathy.

Introduction It has been suggested that the syndrome of inappropriate antidiuretic hormone secretion might occur in Wernicke's encephalopathy (Shalhoub and Antoniou, 1969; Ebels, 1978; Leading Article, 1979). However, the authors are unaware of published evidence for this although Ebels mentions he has such evidence in a patient. A case is reported in which reversal of the syndrome of inappropriate antidiuretic hormone secretion occurred with intravenous vitamin B complex.